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Disease facts & stats

5 sourced facts about diseases and the leading causes of death, each with the context behind the number. 4 more are in today's round and appear here after it closes.

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Going deeper

Heart disease is the top killer in the US. About how many Americans died of it in 2024?

Answer683,491 deaths

Heart disease remains the leading cause of death in the United States by a wide margin.

Source: CDC NCHS FastStats (2024) cdc.gov

Cancer is the second-leading cause of US deaths. About how many died of it in 2024?

Answer619,876 deaths

Cancer killed nearly 620,000 Americans in 2024, just behind heart disease.

Source: CDC NCHS FastStats (2024) cdc.gov

About how many total deaths did the top 10 leading causes account for in the US in 2024?

Answerabout 2.18 million (sum of the 10 listed 2024 causes = 2,179,957; page does not state a single combined total)

The top 10 causes of death together accounted for roughly 2.4 million deaths in the US.

Source: CDC NCHS FastStats (2024) cdc.gov

Worldwide, what share of all deaths in 2021 came from just the top 10 causes?

Answer57%

The top 10 causes accounted for 39 million of the 68 million deaths worldwide that year.

Source: World Health Organization (2021) who.int

Expert level

COVID-19 became the world's #2 cause of death in 2021. About how many people died from it that year?

Answerabout 8.8 million

COVID-19 killed an estimated 8.8 million people worldwide in 2021 alone, per WHO estimates.

Source: World Health Organization (2021) who.int

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